Emergency responders will now have a way to treat people for cyanide poisoning immediately at the scene of a fire, accident or other emergency as well as in the emergency department of a hospital. 'Treating cyanide poisoning as soon as possible after exposure is critical to survival. Additional causes may include accidental or intentional ingestion or exposure during industrial accidents or a terrorist attack involving cyanide.'We are very pleased with the FDA's decision to approve Cyanokit,' said Christy Taylor, Senior Vice President of Marketing, Sales and Business Development for Dey, LP. It is the first cyanide antidote to be approved in the United States in several decades.In the U.S., cyanide poisoning is primarily caused by smoke inhalation during closed space structural fires. Dey, LP expects Cyanokit to be available early in 2007.Cyanokit's unique mechanism of action makes possible its use in a pre- hospital or hospital setting. Dey, LP is located in Napa, CA and will market Cyanokit in the US market. Food and Drug Administration (FDA) has approved Cyanokit(R) (hydroxocobalamin for injection), for the treatment of known or suspected cyanide poisoning.EMD Pharmaceuticals completed the submission of a New Drug Application (NDA) for Cyanokit(R) (hydroxocobalamin for injection) to the FDA in June of 2006.

Affiliates of Merck KGaA of Darmstadt, Germany, jointly announced today that the U.S.

Hydroxocobalamin cyanide mechanism